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'Avatar: Fire and Ash' trailer

The trailer for James Cameron's "Avatar: Fire and Ash" starring Sam Worthington, Zoe Salda?a, Kate Winslet, Sigourney Weaver and Stephen Lang.

Filmmaker James Cameron blasted President Donald Trump as the "most narcissistic a------ in history since f------ Nero" in an interview discussing his latest film and the future of humanity.

Cameron, best known for directing "Titanic" and "Avatar," voiced frustration with the Trump administration’s decision to roll back environmental protections. He argued the White House is helping to send the human race "backwards."

"I’m not frustrated that ‘Avatar’ isn’t solving it," Cameron told The Hollywood Reporter while discussing his concerns about climate change.

James Cameron attends the European premiere of 20th Century Studios’ "Avatar: Fire and Ash" in Boulogne-Billancourt, France, on Dec. 5. (Lyvans Boolaky/Getty Images for Disney)

"I’m frustrated because the human race seems to be delusional about what they think is going to happen next. We are going backwards," Cameron said.

According to the Hollywood Reporter, Cameron described Trump as the "most narcissistic a------ in history since f------ Nero." He added, "Yeah, you can quote that." 

Fox News Digital reached out to the White House for comment.

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Cameron warned that he sees environmental decline, artificial intelligence and shifting moviegoing habits as emerging threats to humanity and Hollywood.

"Who’s to say we wouldn’t be going backwards even faster if it wasn’t for these films? There isn’t an alternative Earth without ‘Avatar’ we can point to and say, ‘It made this measurable difference,’" Cameron said, adding that he believes his films are on the "right side of history."

James Cameron attends the "Avatar: Fire And Ash" photocall in Paris, France, on Dec. 4. (Pascal Le Segretain/Getty Images)

Cameron has been a frequent critic of Trump, telling New Zealand outlet Stuff that he found the president’s re-election "horrifying" in January.

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He also tied his environmental warnings to what he sees as the growing danger of artificial intelligence. Cameron has previously cautioned that AI could become a destructive force, both globally and within the film industry. 

"I’m worried there’s going to be a generation that thinks they could make a movie without an actor," Cameron cautioned.